SCHEMBL10060772

SCHEMBL10060772

c1ccc(-c2cccc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7cccc(-c8cccc(-c9ccccc9)n8)n7)c6c54)n3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47
COMT P21964 1/20 0.38
ASIC3 Q9UHC3 1/20 0.38
KDM4E B2RXH2 3/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
DUSP3 P51452 1/20 0.35
MCL1 Q07820 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
USP30 Q70CQ3 2/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
FTO Q9C0B1 1/20 0.32
HTR1A P08908 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027537 0.97 MEN1 (0.46) MEN1RAB9AKMT2ACOMTASIC3
SCHEMBL10061802 0.95 L3MBTL1 (0.44) MEN1RAB9AKMT2ACOMTASIC3
SCHEMBL17248193 0.94 MEN1 (0.43) MEN1RAB9AKMT2ACOMTASIC3
SCHEMBL12036280 0.92 L3MBTL1 (0.46) MEN1RAB9AKMT2ACOMTASIC3
SCHEMBL15128407 0.91 MEN1 (0.48) MEN1RAB9AKMT2ACOMTASIC3
SCHEMBL5114706 0.91 MEN1 (0.53) MEN1RAB9AKMT2ACOMTASIC3
SCHEMBL12036269 0.91 MEN1 (0.38) MEN1RAB9AKMT2ACOMTKDM4E
SCHEMBL12036278 0.89 DUSP3 (0.39) MEN1KMT2AKDM4EATML3MBTL1
SCHEMBL19849176 0.89 L3MBTL1 (0.44) MEN1RAB9AKMT2ACOMTASIC3
SCHEMBL17248194 0.89 L3MBTL1 (0.40) MEN1RAB9AKMT2ACOMTASIC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4039774-B1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-09-20 EP disclosed
EP-2415772-B1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL & SUMIKIN CHEM CO (JP) 2018-05-16 EP disclosed
EP-3176241-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
EP-2511360-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-10-17 EP disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
EP-2415772-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Nippon Steel Chemical Co., Ltd. (JP) 2012-02-08 EP disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT LEF1, EML4, TEAD1 MEN1 2470/4885RAB9A 4391/4885KMT2A 2796/4885
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME LEF1, ELOC, ALG3 MEN1 381/4885RAB9A 1574/4885KMT2A 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.