Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703691 | 0.82 | TLR8 (0.54) | CYP1A2TLR7 | |
| SCHEMBL9431635 | 0.75 | PLAU (0.50) | DCPSLTA4HMAPK14SMN1; SMN2PDE5A | |
| SCHEMBL6537540 | 0.74 | PLAU (0.51) | DCPSADORA1ADORA3ADORA2ALTA4H | |
| SCHEMBL1010420 | 0.74 | LMNA (0.44) | DCPSADORA1ADORA3ADORA2ASMN1; SMN2 | |
| SCHEMBL1007693 | 0.74 | TLR7 (0.49) | DCPSADORA1ADORA3ADORA2ASMN1; SMN2 | |
| SCHEMBL1924839 | 0.74 | TLR7 (0.48) | ADORA2ATLR7 | |
| SCHEMBL1006095 | 0.73 | ADORA1 (0.49) | DCPSADORA1ADORA3ADORA2ALTA4H | |
| SCHEMBL4990365 | 0.73 | SLC40A1 (0.50) | LTA4HMAPK14MPOSMN1; SMN2STAT3 | |
| SCHEMBL2400921 | 0.72 | DCPS (0.60) | DCPSADORA1ADORA3ADORA2ALTA4H | |
| SCHEMBL1486448 | 0.72 | DCPS (0.60) | DCPSADORA1ADORA3ADORA2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130379-A1 | BENZONAPTHYRIDINE COMPOSITIONS AND USES THEREOF | NOVARTIS AG (CH) | 2011-10-20 | — | — | WO | disclosed |
| EP-2268618-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009111337-A1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | IRM LLC (BM) | 2009-09-11 | — | — | WO | disclosed |