Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026825 | 0.79 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL25887904 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL15736702 | 0.72 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL22728287 | 0.72 | RIPK1 (0.37) | RIPK1 | |
| SCHEMBL15734325 | 0.71 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL1547845 | 0.71 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL28156144 | 0.70 | RIPK1 (0.42) | RIPK1 | |
| SCHEMBL17552749 | 0.68 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL20132763 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL10193863 | 0.67 | TAAR1 (0.40) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022040-A1 | ANTIMICROBIALS | AMPLYX PHARMACEUTICALS, INC. | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022040-A1 | ANTIMICROBIALS | PAM, MPO, OXA1L | RIPK1 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.