SCHEMBL1006136

SCHEMBL1006136

OCCCCCC1CCCCC1

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.60
CYP1A2 P05177 1/20 0.52
KDM5A P29375 3/20 0.43
PHF8 Q9UPP1 3/20 0.43
KDM2A Q9Y2K7 3/20 0.43
KDM4C Q9H3R0 2/20 0.43
KDM4A O75164 1/20 0.43
EPHX1 P07099 2/20 0.42
NAAA Q02083 2/20 0.40
GPR84 Q9NQS5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4281112 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL5542454 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL11470937 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL1006265 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL1007122 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL1006966 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL25310908 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL1007371 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL330182 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL6817084 1.00 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320175-A1 Acetoacetate Based Ketals ARXADA AG (CH) 2025-10-16 US claimed
US-20250066408-A1 Polyol-Derived Compounds ARXADA AG (CH) 2025-02-27 US claimed
US-20250002446-A1 Acetoacetate Based Ketals ARXADA AG (CH) 2025-01-02 US claimed
US-20240336646-A1 Polyol-Derived Compounds ARXADA AG (CH) 2024-10-10 US claimed
EP-4412987-A1 ACETOACETATE BASED KETALS Arxada AG (CH) 2024-08-14 EP claimed
EP-4405324-A1 POLYOL-DERIVED COMPOUNDS Arxada AG (CH) 2024-07-31 EP claimed
WO-2023094654-A1 ACETOACETATE BASED KETALS ARXADA AG (CH) 2023-06-01 WO claimed
WO-2023083570-A1 POLYOL-DERIVED COMPOUNDS ARXADA AG (CH) 2023-05-19 WO claimed
CN-110282829-B Livestock breeding wastewater treatment method based on double-membrane solar technology 兴源环境科技股份有限公司 2021-10-08 CN claimed
CN-1830987-A Ammonium salt of cyclohexanpentol and its use UNIV SICHUAN NORMAL (CN) 2006-09-13 CN claimed
CN-1830986-A Method for preparing ammonium salts of cyclohexanpentol phosphate ester UNIV SICHUAN NORMAL (CN) 2006-09-13 CN claimed
EP-1608350-A1 METHODS OF PREVENTING, TREATING AND DIAGNOSING DISORDERS OF PROTEIN AGGREGATION Ellipsis Biotherapeutics Corporation (CA) 2005-12-28 EP claimed
WO-2004075882-A1 METHODS OF PREVENTING, TREATING AND DIAGNOSING DISORDERS OF PROTEIN AGGREGATION ELLIPSIS BIOTHERAPEUTICS CORPORATION (CA) 2004-09-10 WO claimed
US-12564551-B2 Composition or oat extract comprising avenanthramide and β-glucan SYMRISE AG (DE) 2026-03-03 US disclosed
US-20250320175-A1 Acetoacetate Based Ketals ARXADA AG (CH) 2025-10-16 US disclosed
US-20250066408-A1 Polyol-Derived Compounds ARXADA AG (CH) 2025-02-27 US disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 EP disclosed
US-4418058-A ANTIBACTERIAL AGENTS SHIONOGI & CO., LTD. (JP) 1983-11-29 US disclosed
US-3956224-A Preparation of powdered crosslinked polyalkylene oxides UNION CARBIDE CORPORATION (US) 1976-05-11 US disclosed
US-3887590-A Azido cyclohexanepentol derivative LABAZ 1975-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336646-A1 Polyol-Derived Compounds PARG, SQLE, PARN SIGMAR1 3251/4885CYP1A2 518/4885KDM5A 2178/4885
US-12564551-B2 Composition or oat extract comprising avenanthramide and β-glucan CUTA, HLA-A, OAT SIGMAR1 455/4885CYP1A2 892/4885KDM5A 4043/4885
US-20250002446-A1 Acetoacetate Based Ketals KYAT1, KAT5, ALDOA SIGMAR1 4086/4885CYP1A2 1156/4885KDM5A 445/4885
US-20250320175-A1 Acetoacetate Based Ketals KYAT1, KAT5, ALDOA SIGMAR1 4086/4885CYP1A2 1156/4885KDM5A 445/4885
US-20250066408-A1 Polyol-Derived Compounds PARG, SQLE, PARN SIGMAR1 3251/4885CYP1A2 518/4885KDM5A 2178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.