Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 9/20 | 0.51 |
| ▸ | BACE1 | P56817 | 8/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608597 | 0.84 | JUN (0.57) | GSK3BBACE1HDAC1HDAC2HDAC8 | |
| SCHEMBL608596 | 0.84 | JUN (0.57) | GSK3BBACE1HDAC1HDAC2HDAC8 | |
| SCHEMBL10061363 | 0.74 | MMP8 (0.74) | MMP9GSK3BBACE1HDAC1HDAC2 | |
| SCHEMBL10061348 | 0.73 | BACE1 (0.53) | MMP9GSK3BBACE1HDAC1HDAC2 | |
| SCHEMBL9907006 | 0.73 | HDAC1 (0.67) | GSK3BBACE1HDAC1HDAC2HDAC8 | |
| Dimethylcurcumin SCHEMBL29354872 | 0.71 | HDAC1 (0.78) | GSK3BBACE1HDAC1HDAC2HDAC8 | |
| Dimethylcurcumin SCHEMBL3686107 | 0.71 | HDAC1 (0.78) | GSK3BBACE1HDAC1HDAC2HDAC8 | |
| Dimethylcurcumin SCHEMBL3487103 | 0.71 | HDAC1 (0.78) | GSK3BBACE1HDAC1HDAC2HDAC8 | |
| Dimethylcurcumin SCHEMBL3487105 | 0.71 | HDAC1 (0.78) | GSK3BBACE1HDAC1HDAC2HDAC8 | |
| SCHEMBL16062435 | 0.71 | MMP9 (0.65) | MMP9BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | MMP9 3662/4885GSK3B 3394/4885BACE1 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.