Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681637 | 0.92 | PTPN1 (0.46) | ALBPPARAPTPN1MAOBABCG2 | |
| SCHEMBL9681641 | 0.92 | PTPN1 (0.46) | ALBPPARAPTPN1MAOBABCG2 | |
| SCHEMBL9317129 | 0.88 | POLB (0.58) | ALBHDAC3STAT3HDAC4HDAC1 | |
| SCHEMBL20024737 | 0.87 | PPARA (0.58) | ALBHDAC3STAT3HDAC4HDAC1 | |
| SCHEMBL9318756 | 0.86 | THRB (0.47) | ALBHDAC3STAT3HDAC4HDAC1 | |
| SCHEMBL2719046 | 0.83 | PTGS2 (0.44) | GAAGPR119 | |
| SCHEMBL9681054 | 0.80 | PTPN1 (0.47) | ALBPPARAPTPN1MAOB | |
| SCHEMBL9681048 | 0.80 | PTPN1 (0.47) | ALBPPARAPTPN1MAOB | |
| SCHEMBL20024746 | 0.80 | PPARA (0.51) | ALBPPARAPPARGPTPN1 | |
| SCHEMBL9317383 | 0.80 | POLB (0.48) | ALBPPARAPTPN1MAOBABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2218764-B1 | Chiral reactive mesogen mixture | MERCK PATENT GMBH (DE) | 2012-01-18 | — | — | EP | disclosed |
| US-8021571-B2 | Chiral reactive mesogen mixture | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-09-20 | — | — | US | disclosed |
| US-8021571-B2 | Chiral reactive mesogen mixture | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-09-20 | — | — | US | disclosed |
| US-20100208191-A1 | CHIRAL REACTIVE MESOGEN MIXTURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-08-19 | — | — | US | disclosed |
| US-20100208191-A1 | CHIRAL REACTIVE MESOGEN MIXTURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-08-19 | — | — | US | disclosed |
| EP-2218764-A1 | Chiral reactive mesogen mixture | Merck Patent GmbH (DE) | 2010-08-18 | — | — | EP | disclosed |