Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681054 | 1.00 | PTPN1 (0.47) | PTPN1PTGS2PTGS1CHRNB4CHRNA3 | |
| SCHEMBL4390921 | 0.90 | ALDH1A1 (0.50) | PTGS2PTGS1CYP3A4SMN1; SMN2NR1I2 | |
| SCHEMBL20024728 | 0.83 | ALDH1A1 (0.58) | PTGS2PTGS1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9681641 | 0.82 | PTPN1 (0.46) | PTPN1PTGS2PTGS1CHRNB4CHRNA3 | |
| SCHEMBL9681637 | 0.82 | PTPN1 (0.46) | PTPN1PTGS2PTGS1CHRNB4CHRNA3 | |
| SCHEMBL29771378 | 0.81 | APP (0.50) | PTGS2PTGS1CYP3A4SMN1; SMN2NR1I2 | |
| SCHEMBL10061395 | 0.80 | ALB (0.49) | PTPN1PPARAALBMAOB | |
| SCHEMBL9190264 | 0.80 | ALDH1A1 (0.61) | PTGS2PPARASMN1; SMN2NR1I2 | |
| SCHEMBL9318533 | 0.79 | THRB (0.56) | PTPN1PTGS2PTGS1PPARAALB | |
| SCHEMBL9318531 | 0.79 | THRB (0.56) | PTPN1PTGS2PTGS1PPARAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464904-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |
| US-5029979-A | Optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1991-07-09 | — | — | US | disclosed |