Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681637 | 1.00 | PTPN1 (0.46) | PTPN1KDM4EMEN1LMNATTR | |
| SCHEMBL10061395 | 0.92 | ALB (0.49) | PTPN1PPARAALBMAOBABCG2 | |
| SCHEMBL2719046 | 0.91 | PTGS2 (0.44) | MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL20024746 | 0.88 | PPARA (0.51) | PTPN1KDM4EMEN1LMNATTR | |
| SCHEMBL9317383 | 0.87 | POLB (0.48) | PTPN1PPARAALBMAOBPTGS1 | |
| SCHEMBL9317387 | 0.87 | POLB (0.48) | PTPN1PPARAALBMAOBPTGS1 | |
| SCHEMBL9318531 | 0.85 | THRB (0.56) | PTPN1PPARAALBMAOBPTGS1 | |
| SCHEMBL9318533 | 0.85 | THRB (0.56) | PTPN1PPARAALBMAOBPTGS1 | |
| SCHEMBL9681048 | 0.82 | PTPN1 (0.47) | PTPN1CYP3A4SMN1; SMN2PPARAALB | |
| SCHEMBL9681054 | 0.82 | PTPN1 (0.47) | PTPN1CYP3A4SMN1; SMN2PPARAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464904-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1992-01-08 | — | — | EP | disclosed |
| US-5029979-A | Optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1991-07-09 | — | — | US | disclosed |