SCHEMBL10061608

SCHEMBL10061608

c1ccc(-n2c3ccccc3c3ccc4c5ccccc5n(-c5cccc(-c6cccc(-n7c8ccccc8c8ccccc87)c6)n5)c4c32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
GAA P10253 2/20 0.36
IL1R1 P14778 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
PDE10A Q9Y233 1/20 0.33
CNR1 P21554 1/20 0.33
MCL1 Q07820 2/20 0.32
PTPN1 P18031 1/20 0.32
COMT P21964 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31
MAPK8 P45983 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17248295 0.99 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12036295 0.96 L3MBTL1 (0.42) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12036274 0.96 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL14208845 0.94 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL14924744 0.94 KDM4E (0.36) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12690802 0.94 KDM4E (0.38) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL10061801 0.93 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL26472847 0.93 ATM (0.38) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL12036280 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL19978774 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2415772-B1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL & SUMIKIN CHEM CO (JP) 2018-05-16 EP disclosed
EP-3176241-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
EP-2415772-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Nippon Steel Chemical Co., Ltd. (JP) 2012-02-08 EP disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT LEF1, EML4, TEAD1 L3MBTL1 155/4885KDM4E 2765/4885ATM 2146/4885
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME LEF1, ELOC, ALG3 L3MBTL1 1570/4885KDM4E 1479/4885ATM 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.