SCHEMBL10061813

SCHEMBL10061813

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5cc6c7ccccc7n(-c7cccc(-c8cc(-c9ccccc9)cc(-c9ccccc9)n8)n7)c6cc54)n3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
RAB9A P51151 1/20 0.38
CYP19A1 P11511 1/20 0.36
ACHE P22303 1/20 0.33
KDM4E B2RXH2 4/20 0.33
DHODH Q02127 2/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
ATM Q13315 1/20 0.33
ADORA1 P30542 2/20 0.32
COMT P21964 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2B P29275 1/20 0.32
MCL1 Q07820 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.31
LMNA P02545 2/20 0.31
HPGD P15428 2/20 0.31
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060873 0.96 MEN1 (0.39) MEN1KMT2ARAB9ACYP19A1ACHE
SCHEMBL10061620 0.95 L3MBTL1 (0.42) MEN1KMT2ARAB9ACYP19A1ACHE
SCHEMBL10061797 0.92 MEN1 (0.46) MEN1KMT2ARAB9AACHEKDM4E
SCHEMBL20865089 0.92 MEN1 (0.40) MEN1KMT2ARAB9ACYP19A1ACHE
SCHEMBL20865096 0.92 MEN1 (0.40) MEN1KMT2ARAB9ACYP19A1ACHE
SCHEMBL10061049 0.91 L3MBTL1 (0.43) MEN1KMT2ARAB9ACYP19A1ACHE
SCHEMBL23204634 0.91 MEN1 (0.39) MEN1KMT2ARAB9ACYP19A1ACHE
SCHEMBL20865204 0.91 MEN1 (0.39) MEN1KMT2ARAB9ACYP19A1ACHE
SCHEMBL10027589 0.89 MEN1 (0.44) MEN1KMT2ARAB9AACHEKDM4E
SCHEMBL20865099 0.89 KDM4E (0.41) MEN1KMT2ARAB9ACYP19A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2415772-B1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL & SUMIKIN CHEM CO (JP) 2018-05-16 EP disclosed
EP-3176241-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
US-8389131-B2 Material for use in phosphorescent device and organic electroluminescent device using same NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-03-05 US disclosed
EP-2511360-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-10-17 EP disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
EP-2415772-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Nippon Steel Chemical Co., Ltd. (JP) 2012-02-08 EP disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2011-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT LEF1, EML4, TEAD1 MEN1 2470/4885KMT2A 2796/4885RAB9A 4391/4885
US-20110315975-A1 MATERIAL FOR USE IN PHOSPHORESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME LEF1, ELOC, ALG3 MEN1 381/4885KMT2A 1530/4885RAB9A 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.