Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712926 | 0.88 | TAAR1 (0.50) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL5431489 | 0.84 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL256804 | 0.81 | TAAR1 (0.48) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL13465565 | 0.79 | GABRA1 (0.39) | TAAR1HTR1AADRA1DADRA1AADRA1B | |
| Lithium SCHEMBL18580003 | 0.79 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL18580002 | 0.79 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| Fluoride SCHEMBL28760317 | 0.79 | TAAR1 (0.46) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL4315585 | 0.78 | TAAR1 (0.50) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1568868 | 0.77 | TAAR1 (0.45) | TAAR1MAOBADRA2AADRA2BADRA2C | |
| SCHEMBL11987565 | 0.76 | IDO1 (0.64) | TAAR1ACHECHRM2IDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106608840-B | A method of preparing imine compound | 中国科学院大连化学物理研究所 | 2019-01-08 | — | — | CN | disclosed |
| US-8309733-B2 | Imino derivatives, methods for producing the same and insecticides containing the same | Meji Seika Pharma Co., Ltd. (JP) | 2012-11-13 | — | — | US | disclosed |
| EP-2503393-A1 | Method for preparation of lithographic printing plate | Fujifilm Corporation (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-20120165559-A1 | Compounds Having a Physiological Effect | V. MANE FILS (FR) | 2012-06-28 | — | — | US | disclosed |
| US-20110172433-A1 | NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| WO-2010122239-A1 | COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT | V. MANE FILS (FR) | 2010-10-28 | — | — | WO | disclosed |
| US-7642339-B2 | Hepatitis C; 1-benzyloxycarbonylamino-2-vinyl-cyclopropyl)-phenyl-phosphinic acid ethyl ester | GILEAD SCIENCES, INC. (US) | 2010-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172433-A1 | NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME | CNOT9, CBR1, CBR3 | TAAR1 226/4885MAOB 3098/4885ADRA2A 1694/4885 |
| US-20120165559-A1 | Compounds Having a Physiological Effect | NPPA, CYP11B2, SHBG | TAAR1 1227/4885MAOB 365/4885ADRA2A 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.