Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006249 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL2483554 | 0.79 | SIGMAR1 (0.59) | SIGMAR1CYP2D6KMT2AALDH1A1POLB | |
| SCHEMBL3550104 | 0.79 | SIGMAR1 (0.59) | SIGMAR1CYP2D6KMT2AALDH1A1POLB | |
| SCHEMBL29156287 | 0.78 | SIGMAR1 (0.54) | SIGMAR1CYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL29156290 | 0.78 | SIGMAR1 (0.54) | SIGMAR1CYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL2454180 | 0.75 | SIGMAR1 (0.50) | SIGMAR1CYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL11876909 | 0.75 | SIGMAR1 (0.50) | SIGMAR1CYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL2852187 | 0.74 | SIGMAR1 (0.61) | SIGMAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4849306 | 0.74 | SIGMAR1 (0.61) | SIGMAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4855673 | 0.74 | SIGMAR1 (0.61) | SIGMAR1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863271-B2 | 2-aminobenzoxazole carboxamides as 5HT3 modulators | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | AMR TECHNOLOGY, INC. (US) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255114-A1 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | HTR3E, HTR3C, HTR3A | SIGMAR1 834/4885CYP2D6 310/4885CYP2C9 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.