Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121604 | 0.84 | L3MBTL3 (0.34) | L3MBTL1L3MBTL3ALDH1A1TP53BP1OPRM1 | |
| SCHEMBL1799353 | 0.83 | L3MBTL3 (0.39) | L3MBTL1L3MBTL3ALDH1A1MAPK1LMNA | |
| Tert-Butyl Formate SCHEMBL28785143 | 0.82 | TDP1 (0.38) | L3MBTL1L3MBTL3ALDH1A1ALOX15TP53BP1 | |
| Ethoxycarbonyl Group SCHEMBL27794623 | 0.82 | L3MBTL3 (0.33) | L3MBTL1L3MBTL3ALDH1A1TP53BP1MAPK1 | |
| Hydrochloric Acid SCHEMBL3665053 | 0.81 | L3MBTL3 (0.33) | L3MBTL1L3MBTL3ALDH1A1TP53BP1MAPK1 | |
| SCHEMBL6628090 | 0.79 | OPRM1 (0.43) | L3MBTL1L3MBTL3ALDH1A1MAPK1OPRM1 | |
| SCHEMBL4213726 | 0.79 | MAPK1 (0.43) | L3MBTL1L3MBTL3TP53BP1MAPK1OPRM1 | |
| SCHEMBL10203442 | 0.78 | KDM4E (0.43) | ALDH1A1ALOX15 | |
| SCHEMBL13240324 | 0.78 | KDM4E (0.43) | ALDH1A1ALOX15 | |
| SCHEMBL10203440 | 0.78 | KDM4E (0.43) | ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-31 | — | — | US | disclosed |
| EP-4384493-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |
| WO-2012020813-A1 | FUSED-RING PYRROLIDINE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | L3MBTL1 1984/4885L3MBTL3 2279/4885ALDH1A1 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.