Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201810 | 0.81 | KDM4E (0.58) | MAPTKMT2AKDM4EZDHHC20ZDHHC2 | |
| SCHEMBL14431193 | 0.80 | — | — | |
| SCHEMBL10068433 | 0.79 | CASP2 (0.41) | MAPTKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16309302 | 0.78 | ZDHHC20 (0.61) | MAPTKMT2AKDM4EZDHHC20ZDHHC2 | |
| SCHEMBL4855765 | 0.78 | — | — | |
| SCHEMBL3897978 | 0.78 | — | — | |
| SCHEMBL4855151 | 0.76 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL9363613 | 0.76 | CA12 (0.50) | MAPTKMT2ACA12CA2CA3 | |
| SCHEMBL23505654 | 0.75 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2 | |
| SCHEMBL14332259 | 0.75 | ZDHHC20 (0.68) | ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3161114-B1 | MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS | LUBRIZOL CORP (US) | 2018-06-06 | — | — | EP | disclosed |
| US-20170096613-A1 | MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS | THE LUBRIZOL CORPORATION | 2017-04-06 | — | — | US | disclosed |
| WO-2015200592-A1 | MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS | THE LUBRIZOL CORPORATION (US) | 2015-12-30 | — | — | WO | disclosed |
| EP-2398876-B1 | OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS | LUBRIZOL CORP (US) | 2014-11-19 | — | — | EP | disclosed |
| US-20120021958-A1 | Oxalic Acid Bis-Amides or Amide-Ester as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010096321-A1 | OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |