Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24760765 | 0.81 | ZDHHC20 (0.55) | CASP2TSHRMAPTNAAAKMT2A | |
| SCHEMBL10068437 | 0.80 | KDM4E (0.38) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10068434 | 0.80 | KDM4E (0.38) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10063646 | 0.79 | MAPT (0.43) | MAPTKMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13201810 | 0.76 | KDM4E (0.58) | TSHRMAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14431193 | 0.75 | — | — | |
| SCHEMBL18752932 | 0.75 | ECE1 (0.46) | TSHRMAPTL3MBTL1FAAHCNR1 | |
| SCHEMBL3897978 | 0.73 | — | — | |
| SCHEMBL3897974 | 0.73 | MAPT (0.32) | MAPT | |
| SCHEMBL4855765 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778858-B2 | Amine derivatives as friction modifiers in lubricants | THE LUBRIZOL CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-20120015855-A1 | Amine Derivatives as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION | 2012-01-19 | — | — | US | disclosed |
| WO-2010096325-A1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |