Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1900471 | 0.83 | KDM4E (0.82) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL10063646 | 0.81 | MAPT (0.43) | KDM4EMAPK1HIF1AALDH1A1MAPT | |
| SCHEMBL21306389 | 0.80 | PAOX (0.74) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL4752158 | 0.80 | ZDHHC20 (0.62) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL4855765 | 0.79 | — | — | |
| SCHEMBL2128046 | 0.78 | PAOX (0.78) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL19961838 | 0.78 | PAOX (0.78) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL4855151 | 0.77 | ZDHHC20 (0.64) | PAOXTSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL14910879 | 0.77 | KDM4E (0.65) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL860791 | 0.77 | KDM4E (0.94) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398873-B1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | LUBRIZOL CORP (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20100210490-A1 | Amine Derivatives as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION (US) | 2010-08-19 | — | — | US | disclosed |