Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004859 | 0.84 | NR1H2 (0.40) | ACHEALDH1A1KDM4EMAPT | |
| SCHEMBL1007352 | 0.77 | ACHE (0.42) | ACHEMAPT | |
| SCHEMBL1004591 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2HPGDATM | |
| SCHEMBL16237303 | 0.65 | TSHR (0.46) | ALDH1A1KDM4ESMN1; SMN2ATMNPSR1 | |
| SCHEMBL1003585 | 0.65 | CYP1A2 (0.45) | ACHEKDM4ENPC1MAPTRAB9A | |
| SCHEMBL1003642 | 0.61 | NR1H2 (0.41) | ALDH1A1KDM4EMAPT | |
| SCHEMBL4458334 | 0.60 | ACHE (0.45) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL18990255 | 0.59 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2HPGDMAPT | |
| SCHEMBL31300761 | 0.58 | XDH (0.47) | ALDH1A1KDM4ESMN1; SMN2NPSR1MAPT | |
| SCHEMBL23617815 | 0.56 | ACHE (0.60) | ACHEALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |