Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056066 | 0.88 | KLK7 (0.39) | ACHEABCB1PSEN1PSEN2APH1B | |
| SCHEMBL1006400 | 0.77 | ACHE (0.38) | ACHEMAPT | |
| SCHEMBL1004076 | 0.73 | ACHE (0.43) | ACHECYP19A1KMT2AMAOB | |
| SCHEMBL1065113 | 0.68 | HDAC1 (0.61) | ACHEHDAC1CYP19A1 | |
| SCHEMBL1004591 | 0.67 | ALDH1A1 (0.37) | TSHR | |
| SCHEMBL24362751 | 0.67 | CYP26A1 (0.49) | CYP19A1 | |
| SCHEMBL16194380 | 0.67 | CYP19A1 (0.49) | ABCB1HDAC1CYP19A1MEN1TSHR | |
| SCHEMBL15700137 | 0.66 | ACHE (0.80) | ACHE | |
| SCHEMBL1007354 | 0.66 | FKBP1A (0.39) | ACHEPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30667087 | 0.65 | CYP19A1 (0.62) | ACHECYP19A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |