Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064200 | 0.97 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL10064726 | 0.93 | LMNA (0.43) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL14165125 | 0.91 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL10064718 | 0.89 | HPGD (0.34) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL10064385 | 0.84 | KDM4E (0.38) | ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL10064294 | 0.83 | HTT (0.38) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL14165306 | 0.83 | LMNA (0.40) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL10064276 | 0.83 | LMNA (0.49) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL18373292 | 0.82 | KDM4E (0.36) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B | |
| SCHEMBL13191221 | 0.82 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2012-03-29 | — | — | US | disclosed |
| WO-2010097604-A2 | NEW COMPOUNDS | UCL BUSINESS PLC (GB) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | CFTR, GNB1, GMPS | ALDH1A1 3297/4885KDM4E 3544/4885HPGD 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.