Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.37 |
| ▸ | HEXB | P07686 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14165577 | 0.84 | KDM4E (0.43) | HEXAHEXBRAB9ANPC1TSHR | |
| SCHEMBL10064201 | 0.83 | ALDH1A1 (0.40) | LMNAPKMNPC1TSHRHPGD | |
| SCHEMBL14165390 | 0.82 | RAB9A (0.41) | RAB9ANPC1TSHRHPGDKDM4E | |
| SCHEMBL14165125 | 0.82 | ALDH1A1 (0.34) | LMNAPKMNPC1TSHRHPGD | |
| SCHEMBL4921108 | 0.82 | SCN9A (0.44) | LMNAPKMMEN1KMT2APDCD1 | |
| SCHEMBL14165223 | 0.82 | KDM4E (0.38) | LMNAPKMHEXAHEXBRAB9A | |
| SCHEMBL10064200 | 0.81 | ALDH1A1 (0.41) | LMNAPKMNPC1TSHRHPGD | |
| SCHEMBL10064726 | 0.80 | LMNA (0.43) | LMNAPKMNPC1HPGDKDM4E | |
| SCHEMBL10064294 | 0.80 | HTT (0.38) | LMNARAB9AHPGDKDM4EMEN1 | |
| SCHEMBL18373292 | 0.79 | KDM4E (0.36) | LMNAHPGDKDM4EALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | UCL BUSINESS PLC (GB) | 2008-06-12 | — | — | US | disclosed |
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | UCL BUSINESS PLC (GB) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | CBR3, CBR1, KCNQ3 | LMNA 1393/4885PKM 4011/4885HEXA 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.