SCHEMBL1006436

SCHEMBL1006436

Cc1ccc(-c2ccc(-c3ccc(C)cc3)c(O)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.52
EGFR P00533 1/20 0.47
APP P05067 1/20 0.46
BACE1 P56817 1/20 0.46
EGLN1 Q9GZT9 1/20 0.45
ALOX5 P09917 4/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
COMT P21964 1/20 0.44
PON1 P27169 1/20 0.43
TRPA1 O75762 1/20 0.42
PDK2 Q15119 1/20 0.42
QDPR P09417 1/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
ACHE P22303 1/20 0.42
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22539594 0.92 EGFR (0.58) MCL1EGFRBACE1EGLN1ALOX5
SCHEMBL10068940 0.88 TRPA1 (0.56) MCL1BACE1ALOX5MEN1NPC1
SCHEMBL6067975 0.84 ALOX5 (0.61) BACE1ALOX5MEN1NPC1RAB9A
SCHEMBL1053667 0.83 APP (0.70) MCL1APPALOX5NPC1TRPA1
SCHEMBL14283893 0.82 BACE1 (0.55) MCL1BACE1MEN1NPC1RAB9A
SCHEMBL1007614 0.81 MCL1 (0.52) MCL1APPEGLN1ALOX5TRPA1
SCHEMBL25853004 0.80 ALOX5 (0.57) EGFRBACE1ALOX5MEN1NPC1
SCHEMBL5684857 0.80 TSHR (0.54) BACE1MEN1NPC1RAB9AKMT2A
SCHEMBL19019376 0.80 CNR1 (0.42) MCL1BACE1ALOX5MEN1NPC1
SCHEMBL17251284 0.80 TRPA1 (0.52) MCL1APPBACE1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
US-20220356302-A1 POLYPHENYLENE ETHER COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-11-10 US disclosed
EP-4039728-A1 POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2022-08-10 EP disclosed
CN-110387037-B Polyphenylene ether and process for producing the same 旭化成株式会社 2022-05-13 CN disclosed
CN-110078912-B Continuous pressure filtration washing method for polyphenyl ether 蓝星(北京)技术中心有限公司 2021-11-09 CN disclosed
EP-2628759-B1 POLYPHENYLENE ETHER AS WELL AS RESIN COMPOSITION AND MOLDING THEREOF ASAHI CHEMICAL IND (JP) 2021-06-30 EP disclosed
CN-112812291-A Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2021-05-18 CN disclosed
CN-108017791-B Polyphenylene ether powder and process for producing the same 旭化成株式会社 2021-02-02 CN disclosed
US-8865811-B2 2014-10-21 US disclosed
US-8637631-B2 Polyphenylene ether and method for producing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-01-28 US disclosed
US-20130245182-A1 POLYPHENYLENE ETHER POWDER AND POLYPHENYLENE ETHER RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-09-19 US disclosed
US-20130231430-A1 POLYPHENYLENE ETHER, RESIN COMPOSITION, AND MOLDED BODY OF RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-09-05 US disclosed
EP-2628760-A1 POLYPHENYLENE ETHER POWDER AND POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
EP-2628759-A1 POLYPHENYLENE ETHER AS WELL AS RESIN COMPOSITION AND MOLDING THEREOF Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
US-8445573-B2 Polyphenylene ether resin composition having narrow molecular weight distribution ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-05-21 US disclosed
US-20120309925-A1 POLYPHENYLENE ETHER AND METHOD FOR PRODUCING THE SAME ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-12-06 US disclosed
US-20110166269-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-07-07 US disclosed
EP-2277951-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION Asahi Kasei Chemicals Corporation (JP) 2011-01-26 EP disclosed