SCHEMBL1007614

SCHEMBL1007614

Cc1ccc(-c2ccc(C)c(O)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.52
TSHR P16473 1/20 0.48
CASP1 P29466 1/20 0.48
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
APP P05067 1/20 0.46
TRPA1 O75762 2/20 0.45
ACHE P22303 2/20 0.45
PTGS1 P23219 1/20 0.45
CACNA1C Q13936 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
ALOX5 P09917 3/20 0.44
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47861 0.90 TSHR (0.56) MCL1TSHRCASP1TP53TDP1
SCHEMBL1005170 0.84 ALOX5 (0.64) MCL1TSHRCASP1APPALOX5
SCHEMBL12387990 0.83 APP (0.70) MCL1TSHRCASP1APPTRPA1
SCHEMBL1053667 0.83 APP (0.70) MCL1TP53TDP1APPTRPA1
SCHEMBL14295102 0.83 MCL1 (0.57) MCL1TSHRCASP1TDP1APP
P-Xylene SCHEMBL11826288 0.82 TRPA1 (0.62) TSHRCASP1TP53TDP1TRPA1
SCHEMBL26936632 0.82 ERCC1 (0.47) TSHRCASP1APPTRPA1ACHE
SCHEMBL2364282 0.82 ALOX5 (0.65) TSHRCASP1APPTRPA1ACHE
SCHEMBL1006436 0.81 MCL1 (0.52) MCL1TP53TDP1APPTRPA1
SCHEMBL13695146 0.81 TSHR (0.48) MCL1TSHRCASP1APPTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
CN-114514261-B Polyphenylene ether composition 旭化成株式会社 2024-09-10 CN disclosed
CN-117229495-A Polyphenylene ether, method for producing the same, thermosetting composition, prepreg, and laminate 旭化成株式会社 2023-12-15 CN disclosed
EP-4289823-A1 SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES Medshine Discovery Inc. (CN) 2023-12-13 EP disclosed
EP-4273125-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
CN-112812291-B Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2023-07-18 CN disclosed
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
US-20220356302-A1 POLYPHENYLENE ETHER COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-11-10 US disclosed
EP-4039728-A1 POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2022-08-10 EP disclosed
US-8901222-B2 Polyphenylene ether, resin composition, and molded body of resin composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-12-02 US disclosed
US-8865811-B2 2014-10-21 US disclosed
US-8637631-B2 Polyphenylene ether and method for producing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-01-28 US disclosed
US-20130231430-A1 POLYPHENYLENE ETHER, RESIN COMPOSITION, AND MOLDED BODY OF RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-09-05 US disclosed
EP-2628759-A1 POLYPHENYLENE ETHER AS WELL AS RESIN COMPOSITION AND MOLDING THEREOF Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
US-8445573-B2 Polyphenylene ether resin composition having narrow molecular weight distribution ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-05-21 US disclosed
US-20120309925-A1 POLYPHENYLENE ETHER AND METHOD FOR PRODUCING THE SAME ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-12-06 US disclosed
US-20110166269-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-07-07 US disclosed
EP-2277951-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION Asahi Kasei Chemicals Corporation (JP) 2011-01-26 EP disclosed
US-20100314241-A1 PROCESS FOR THE TREATMENT OF ORGANIC WASTE AND PRODUCT OBTAINED THEREOF TRIDACNA LTD. (IL) 2010-12-16 US disclosed