Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.50 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068940 | 0.86 | TRPA1 (0.56) | ALOX5ACHECA12CA9BACE1 | |
| SCHEMBL278379 | 0.85 | ALOX5 (0.73) | ALOX5ESR2ESR1HSD17B1HSD17B10 | |
| SCHEMBL29615176 | 0.84 | BACE1 (0.56) | ALOX5ACHEESR2ESR1CA12 | |
| SCHEMBL1163817 | 0.84 | BACE1 (0.56) | ALOX5ACHEESR2ESR1CA12 | |
| SCHEMBL1006436 | 0.84 | MCL1 (0.52) | ALOX5ACHECA12CA9BACE1 | |
| SCHEMBL3811869 | 0.83 | ALOX5 (0.70) | ALOX5ESR2ESR1HSD17B1HSD17B10 | |
| SCHEMBL27619639 | 0.82 | ALOX5 (0.56) | ALOX5ESR2ESR1 | |
| SCHEMBL20690490 | 0.82 | ALOX5 (0.56) | ALOX5ACHEESR2ESR1HSD17B1 | |
| SCHEMBL26437159 | 0.81 | TRPA1 (0.56) | ALOX5ACHEESR2ESR1HSD17B10 | |
| SCHEMBL19334620 | 0.81 | ACHE (0.65) | ACHEESR2ESR1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125428-B2 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | WELLA AG (DE) | 2006-10-24 | — | — | US | disclosed |
| EP-1392673-A2 | 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2004-01-29 | — | — | US | disclosed |
| WO-2002096901-A2 | 1,3-DIHYDROXYBENZENE DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-05 | — | — | WO | disclosed |
| EP-0534204-B1 | Base developable negative photoresist and use thereof | IBM (US) | 1997-06-04 | — | — | EP | disclosed |
| EP-0534204-A1 | Base developable negative photoresist and use thereof | International Business Machines Corporation (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0009190-B1 | CURABLE COMPOSITION USEFUL FOR SCREEN-PRINTING, A CURED COATING COMPRISING SAID COMPOSITION AND PROCESS FOR SOLDERING PRINTED CIRCUIT BOARDS USING SAID COMPOSITION | International Business Machines Corporation (US) | 1982-04-28 | — | — | EP | disclosed |
| EP-0009190-A1 | Curable composition useful for screen-printing, a cured coating comprising said composition and process for soldering printed circuit boards using said composition | International Business Machines Corporation (US) | 1980-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040016063-A1 | 1,3-Dihydroxybenzene derivatives and colorants containing said compounds | KRT18, DSP, COL1A1 | ALOX5 3355/4885ACHE 1194/4885ESR2 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.