Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882041 | 0.77 | KMT2A (0.52) | KMT2AL3MBTL1GPR3KDM4ECYP1A2 | |
| SCHEMBL31300314 | 0.75 | LMNA (0.47) | KMT2AL3MBTL1GPR3KDM4ECYP1A2 | |
| SCHEMBL2317712 | 0.75 | LMNA (0.47) | KMT2AL3MBTL1GPR3KDM4ECYP1A2 | |
| SCHEMBL18470455 | 0.74 | KMT2A (1.00) | KMT2AL3MBTL1GPR3KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL638236 | 0.69 | KMT2A (0.44) | KMT2AL3MBTL1KDM4ECYP1A2CYP2A6 | |
| SCHEMBL6328127 | 0.69 | PRMT5 (0.68) | HTTNPSR1LMNAALDH1A1PRMT5 | |
| Hydrochloric Acid SCHEMBL639710 | 0.69 | KMT2A (0.53) | KMT2AL3MBTL1GPR3KDM4ECYP1A2 | |
| SCHEMBL10635206 | 0.69 | KMT2A (0.48) | KMT2AL3MBTL1KDM4ELMNAMEN1 | |
| SCHEMBL2760679 | 0.68 | KMT2A (0.56) | KMT2AL3MBTL1KDM4ELMNACYP3A4 | |
| SCHEMBL2307835 | 0.67 | GOT1 (0.46) | KMT2AL3MBTL1KDM4ECYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10290819-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2019-05-14 | — | — | US | disclosed |
| US-20130284977-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130284977-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012079741-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10290819-B2 | Metal complexes | PICALM, IMMT, IKZF3 | KMT2A 3362/4885L3MBTL1 3693/4885GPR3 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.