Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228 | 0.81 | GAA (0.95) | GAAMAPTSIGMAR1MPOMEN1 | |
| SCHEMBL25432637 | 0.79 | GAA (0.91) | GAAMAPTSIGMAR1MPOMEN1 | |
| SCHEMBL11881258 | 0.79 | GAA (0.91) | GAAMAPTEPHX2SIGMAR1MPO | |
| Ammonia Solution, Strong SCHEMBL23581968 | 0.79 | GAA (0.91) | GAAMAPTSIGMAR1MPOMEN1 | |
| Hydrochloric Acid SCHEMBL1983401 | 0.79 | GAA (1.00) | GAAMAPTSIGMAR1MPOMEN1 | |
| SCHEMBL3272134 | 0.79 | GAA (0.91) | GAAMAPTEPHX2SIGMAR1MPO | |
| SCHEMBL283735 | 0.78 | SIGMAR1 (0.81) | GAAMAPTSMN1; SMN2SIGMAR1ALDH1A1 | |
| SCHEMBL3987506 | 0.75 | SMN1; SMN2 (0.66) | GAAMAPTSMN1; SMN2EPHX2SIGMAR1 | |
| SCHEMBL10478067 | 0.75 | EPHX2 (0.54) | GAAMAPTSMN1; SMN2EPHX2SIGMAR1 | |
| SCHEMBL6031397 | 0.75 | GAA (0.53) | GAAMAPTSMN1; SMN2EPHX2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10290819-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2019-05-14 | — | — | US | disclosed |
| US-20130284977-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130284977-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012079741-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10290819-B2 | Metal complexes | PICALM, IMMT, IKZF3 | GAA 4195/4885MAPT 2442/4885SMN1; SMN2 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.