Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120251 | 0.82 | CA1 (0.50) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 | |
| SCHEMBL2121172 | 0.81 | CA1 (0.49) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 | |
| SCHEMBL12722192 | 0.79 | HTT (0.52) | ALDH1A1TDP1POLBTSHRMEN1 | |
| SCHEMBL12722194 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1POLBTSHRSMN1; SMN2 | |
| SCHEMBL2119806 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1POLBTSHRSMN1; SMN2 | |
| SCHEMBL19878321 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TDP1POLBTSHRSMN1; SMN2 | |
| SCHEMBL2204794 | 0.75 | IMPDH2 (0.40) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL12722185 | 0.75 | HCRTR2 (0.44) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL3651761 | 0.74 | TDP1 (0.70) | TDP1POLBTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL14341846 | 0.74 | CA1 (0.43) | ALDH1A1POLBTSHRRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8460636-B2 | Complex compound and MRI probe made of same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-06-11 | — | — | US | disclosed |
| US-20120093735-A1 | COMPLEX COMPOUND AND MRI PROBE MADE OF SAME | SUZUKI KOJI (JP) | 2012-04-19 | — | — | US | disclosed |
| US-20110165089-A1 | Complex Compound and MRI Probe Made of Same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093735-A1 | COMPLEX COMPOUND AND MRI PROBE MADE OF SAME | KCNN2, KCNN1, KCNN3 | ALDH1A1 4683/4885TDP1 4512/4885POLB 4862/4885 |
| US-20110165089-A1 | Complex Compound and MRI Probe Made of Same | KCNN2, KCNN1, KCNN3 | ALDH1A1 4683/4885TDP1 4512/4885POLB 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.