Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19878371 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL2119806 | 0.83 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDTDP1SMN1; SMN2 | |
| SCHEMBL19878420 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL12722194 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1SMN1; SMN2POLB | |
| SCHEMBL12722192 | 0.80 | HTT (0.52) | ALDH1A1TSHRTDP1NPSR1POLB | |
| SCHEMBL10064630 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1SMN1; SMN2NPSR1 | |
| SCHEMBL3205979 | 0.77 | APP (0.65) | ALDH1A1TSHRAOX1FDPSHPGD | |
| SCHEMBL14023114 | 0.77 | TRPA1 (0.50) | ALDH1A1TSHRHPGDTDP1SMN1; SMN2 | |
| SCHEMBL12722185 | 0.77 | HCRTR2 (0.44) | ALDH1A1TDP1MAPT | |
| SCHEMBL19878350 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRAOX1FDPSHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500860-A1 | COMPOSITION AND METHODS FOR MEASURING ION CHANNEL ACTIVITY IN A CELL | Life Technologies Corporation (US) | 2019-06-26 | — | — | EP | disclosed |
| US-20190187155-A1 | COMPOSITION AND METHODS FOR MEASURING ION CHANNEL ACTIVITY IN A CELL | Life Technologies Corporation | 2019-06-20 | — | — | US | disclosed |
| WO-2018035230-A1 | COMPOSITION AND METHODS FOR MEASURING ION CHANNEL ACTIVITY IN A CELL | Life Technologies Corporation (US) | 2018-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190187155-A1 | COMPOSITION AND METHODS FOR MEASURING ION CHANNEL ACTIVITY IN A CELL | TMCO1, TRPM5, CLIC1 | ALDH1A1 4189/4885TSHR 1734/4885AOX1 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.