SCHEMBL188320

SCHEMBL188320

NC(Cc1cc(F)cc(F)c1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.57
PTGS1 P23219 2/20 0.57
PKM P14618 2/20 0.57
ALPI P09923 1/20 0.57
XIAP P98170 1/20 0.57
HSD17B10 Q99714 4/20 0.53
USP2 O75604 3/20 0.53
KDM4E B2RXH2 2/20 0.53
ALOX15 P16050 2/20 0.53
RECQL P46063 2/20 0.53
HIF1A Q16665 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
EGFR P00533 1/20 0.53
LCK P06239 1/20 0.53
FYN P06241 1/20 0.53
HTR2A P28223 1/20 0.53
PTGS2 P35354 1/20 0.53
CYP2C9 P11712 2/20 0.52
MEN1 O00255 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188321 1.00 SLC7A5 (0.57) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL2129884 1.00 SLC7A5 (0.57) SLC7A5PTGS1PKMALPIXIAP
Glycine SCHEMBL28732579 0.93 SLC7A5 (0.50) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL31524255 0.89 SLC7A5 (0.56) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL10064656 0.89 SLC7A5 (0.56) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL12803446 0.89 SLC7A5 (0.56) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL845968 0.88 SLC7A5 (0.49) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL31537504 0.88 SLC7A5 (0.49) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL22944380 0.88 SLC7A5 (0.49) SLC7A5PTGS1PKMALPIXIAP
SCHEMBL845967 0.88 SLC7A5 (0.49) SLC7A5PTGS1PKMALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117832652-A Additive for aqueous zinc ion battery electrolyte, electrolyte and aqueous zinc ion battery 北京理工大学 2024-04-05 CN claimed
CN-105143245-B Anti-scaling material 耶路撒冷希伯来大学伊森姆研究发展有限公司 2021-02-05 CN claimed
EP-2951195-B1 ANTIFOULING MATERIALS YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) 2020-02-19 EP claimed
EP-3374520-A1 BIOSENSORS Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2018-09-19 EP claimed
WO-2017081684-A1 BIOSENSORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2017-05-18 WO claimed
US-9631100-B2 Antifouling materials YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2017-04-25 US claimed
EP-3046933-A1 CO RTI STATIN ANALOGUES FOR THE TREATMENT OF INFLAMMATORY AND/OR IMMUNE DISEASES BCN Peptides, S.A. (ES) 2016-07-27 EP claimed
US-20160185822-A1 CORTISTATIN ANALOGUES FOR THE TREATMENT OF INFLAMMATORY AND/OR IMMUNE DISEASES BCN PEPTIDES, S.A. (ES) 2016-06-30 US claimed
US-20150368480-A1 ANTIFOULING MATERIALS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2015-12-24 US claimed
EP-2951195-A1 ANTIFOULING MATERIALS Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. (IL) 2015-12-09 EP claimed
WO-2015040089-A1 CO RTI STATIN ANALOGUES FOR THE TREATMENT OF INFLAMMATORY AND/OR IMMUNE DISEASES BCN PEPTIDES S.A. (ES) 2015-03-26 WO claimed
WO-2014118779-A1 ANTIFOULING MATERIALS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2014-08-07 WO claimed
US-8486370-B2 Heterocyclic ligands for integrin imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-16 US claimed
US-20100310455-A1 Heterocyclic Ligands for Integrin Imaging and Therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-09 US claimed
US-20260116855-A1 ORALLY ACTIVE MELANOCORTIN RECEPTOR-4 COMPOUNDS PALATIN TECHNOLOGIES INC (US) 2026-04-30 US disclosed
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR UNIV CALIFORNIA (US) 2026-03-26 US disclosed
EP-4687443-A1 METHOD FOR FUNCTIONALISING A SOLID SUBSTRATE WITH A PEPTIDE CONJUGATE Genepep (FR) 2026-02-11 EP disclosed
EP-0073143-B1 NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES Ryan, James Walter (US) 1985-11-21 EP disclosed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 EP disclosed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100310455-A1 Heterocyclic Ligands for Integrin Imaging and Therapy ITGA1, ITGAL, ITGA4 SLC7A5 258/4885PTGS1 3498/4885PKM 3691/4885
US-20160185822-A1 CORTISTATIN ANALOGUES FOR THE TREATMENT OF INFLAMMATORY AND/OR IMMUNE DISEASES GHSR, GIPR, GHRHR SLC7A5 2543/4885PTGS1 2159/4885PKM 4458/4885
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR PDGFA, DCLRE1A, PDGFRA SLC7A5 2952/4885PTGS1 2338/4885PKM 4637/4885
US-20260116855-A1 ORALLY ACTIVE MELANOCORTIN RECEPTOR-4 COMPOUNDS MC1R, MC3R, MC5R SLC7A5 234/4885PTGS1 1992/4885PKM 3629/4885
US-20150368480-A1 ANTIFOULING MATERIALS PFAS, FLNB, FLNA SLC7A5 2272/4885PTGS1 2521/4885PKM 3572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.