Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813055 | 0.97 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3MAOAMEN1 | |
| SCHEMBL9502046 | 0.87 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3MAOAMEN1 | |
| SCHEMBL31726422 | 0.83 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3MAOAMEN1 | |
| SCHEMBL7621961 | 0.80 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3MAOAMEN1 | |
| SCHEMBL3164479 | 0.78 | NR1H2 (0.41) | SLC6A4MAOAMEN1KMT2ARAB9A | |
| SCHEMBL944380 | 0.78 | CA1 (0.41) | SLC6A4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13026656 | 0.78 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3MAOAMEN1 | |
| SCHEMBL4460695 | 0.77 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3MAOAMEN1 | |
| SCHEMBL83839 | 0.76 | ALDH1A1 (0.58) | SLC6A4SLC6A2SLC6A3MAOAMEN1 | |
| SCHEMBL97582 | 0.76 | CA1 (0.52) | SLC6A4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050523-B | Wear-resistant polyphenylene sulfide material and preparation method thereof | 东莞市曼塔新材料科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117050523-A | Wear-resistant polyphenylene sulfide material and preparation method thereof | 东莞市曼塔新材料科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116987210-A | Cationic chitosan conductive functional auxiliary agent and preparation method and application thereof | 华南农业大学 | 2023-11-03 | — | — | CN | claimed |
| CN-110540526-B | Carane acidyl 1,2, 3-triazole compound and preparation method and application thereof | 广西大学 | 2022-08-30 | — | — | CN | claimed |
| CN-110540526-A | Carane acidyl 1,2, 3-triazole compound and preparation method and application thereof | UNIV GUANGXI | 2019-12-06 | — | — | CN | claimed |
| EP-2145895-B1 | Process for the manufacturing of glycochips | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2013-10-30 | — | — | EP | claimed |
| US-20100035353-A1 | PROCESS FOR THE MANUFACTURING OF GLYCOCHIPS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-02-11 | — | — | US | claimed |
| EP-2145895-A1 | Process for the manufacturing of glycochips | Commissariat à l'Energie Atomique (FR) | 2010-01-20 | — | — | EP | claimed |
| EP-1198455-B1 | PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2- (4-(METHYLSULPHONYL) PHENYL] ETHANONE | LONZA AG (CH) | 2003-12-10 | — | — | EP | claimed |
| US-6566527-B1 | Five-step process; starting with p-(methylthio)benzyl alcohol, chlorination, cyaniding, condensation with 6-methylnicotinic ester, hydrolysis and decarboxylation, and oxidation | MERCK & CO., INC. | 2003-05-20 | — | — | US | claimed |
| US-20030088107-A1 | Process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone | BESSARD YVES (CH) | 2003-05-08 | — | — | US | claimed |
| EP-1198455-A1 | PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2- (4-(METHYLSULPHONYL) PHENYL] ETHANONE | Lonza AG (CH) | 2002-04-24 | — | — | EP | claimed |
| WO-2001007410-A1 | PROCESS FOR PREPARING 1-(6-METHYLPYRIDIN-3-YL)-2-[(4-(METHYLSULPHONYL) PHENYL] ETHANONE | LONZA AG (CH) | 2001-02-01 | — | — | WO | claimed |
| US-5565602-A | REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| US-4248779-A | REACTING CARBONYL SULFIDE WITH A SECONDARY AMINE AND REACTING THE AMINE SALT WITH A HALOHYDROCARBON | IHARA CHEMICAL INDUSTRY COMPANY, LIMITED (JP) | 1981-02-03 | — | — | US | claimed |
| US-20240308989-A1 | PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | ORION CORP (FI) | 2024-09-19 | — | — | US | disclosed |
| US-12030871-B2 | Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors | ORION CORPORATION (FI) | 2024-07-09 | — | — | US | disclosed |
| US-3944600-A | Indenylidene-3-acetic acid process for preparing indene acetic acids | MERCK & CO., INC. (US) | 1976-03-16 | — | — | US | disclosed |
| US-3933947-A | INSECTICIDE, MITICIDE, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |
| US-3931268-A | Methylhydrazinomethyl-substituted benzoic acid amides | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030088107-A1 | Process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone | PTGES2, PTGS1, CYP2J2 | SLC6A4 4580/4885SLC6A2 4640/4885SLC6A3 4748/4885 |
| US-20100035353-A1 | PROCESS FOR THE MANUFACTURING OF GLYCOCHIPS | HGF, HGFAC, HDGF | SLC6A4 3148/4885SLC6A2 3615/4885SLC6A3 3467/4885 |
| US-12030871-B2 | Pyran dervatives as CYP11A1 (cytochrome P450 monooxygenase 11A1) inhibitors | CYP11B1, CYP11B2, CYP4A11 | SLC6A4 1945/4885SLC6A2 4247/4885SLC6A3 3054/4885 |
| US-20240308989-A1 | PYRAN DERIVATIVES AS CYP11A1 (CYTOCHROME P450 MONOOXYGENASE 11A1) INHIBITORS | CYP11B1, CYP11B2, CYP4A11 | SLC6A4 2414/4885SLC6A2 4326/4885SLC6A3 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.