Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130445 | 1.00 | TRPM8 (0.49) | TRPM8BCHECYP3A4NFKB1NFKB2 | |
| SCHEMBL1006524 | 0.86 | AKR1C3 (0.48) | CYP3A4ALDH1A1HTTATMHPGD | |
| SCHEMBL6123027 | 0.83 | ABCG2 (0.56) | CYP3A4NFKB1ALDH1A1THRBATM | |
| SCHEMBL28947529 | 0.83 | ABCG2 (0.56) | CYP3A4NFKB1ALDH1A1THRBATM | |
| SCHEMBL27594469 | 0.82 | THRB (0.49) | TRPM8BCHECYP3A4NFKB1NFKB2 | |
| SCHEMBL29082922 | 0.79 | CYP1B1 (0.42) | CYP3A4GAASMN1; SMN2THRBMAPT | |
| SCHEMBL1004802 | 0.79 | ATM (0.44) | BCHEALDH1A1GAAATMMAPT | |
| SCHEMBL1004800 | 0.79 | ATM (0.44) | BCHEALDH1A1GAAATMMAPT | |
| SCHEMBL13916943 | 0.77 | AKR1C3 (0.49) | ALDH1A1THRBATMMAPTCES2 | |
| SCHEMBL6056036 | 0.77 | AKR1C3 (0.49) | ALDH1A1THRBATMMAPTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7053451-A | — | — | None | — | — | JP | disclosed |
| JP-H0753451-A | ALPHA-OXYCINNAMIC ACID DERIVATIVE, ULTRAVIOLET LIGHT ABSORBER AND COSMETIC CONTAINING THE SAME | KAO CORP | 1995-02-28 | — | — | JP | disclosed |