Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.41 |
| ▸ | ELOC | Q15369 | 1/20 | 0.41 |
| ▸ | ELOB | Q15370 | 1/20 | 0.41 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066201 | 0.95 | PRSS1 (0.49) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL12984633 | 0.85 | APLNR (0.49) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL10065714 | 0.80 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL10066224 | 0.76 | RAMP3 (0.51) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL15832044 | 0.73 | PKM (0.69) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL12972428 | 0.73 | FOLH1 (0.59) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL12743524 | 0.73 | FOLH1 (0.59) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL8121361 | 0.72 | FOLH1 (0.53) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL22803360 | 0.72 | PRSS1 (0.52) | PRSS1PRSS2PRSS3TPSAB1PLG | |
| SCHEMBL13475036 | 0.72 | FOLH1 (0.54) | PRSS1PRSS2PRSS3TPSAB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | BRACCO IMAGING S.P.A. (IT) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | TAGLN2, TTN, TXLNA | PRSS1 2410/4885PRSS2 2765/4885PRSS3 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.