SCHEMBL10066073

SCHEMBL10066073

CC1(C)CCCC(C)(C)N1N=Nc1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 2/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SLC2A1 P11166 1/20 0.32
ATM Q13315 1/20 0.32
HSD11B1 P28845 3/20 0.31
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
NR1I2 O75469 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10033963 0.84 MAPT (0.36) MAPTALDH1A1SMN1; SMN2MAPK1L3MBTL1
SCHEMBL10033970 0.82 ALDH1A1 (0.39) MAPTALDH1A1SMN1; SMN2MAPK1L3MBTL1
SCHEMBL10033969 0.82 ALDH1A1 (0.39) MAPTALDH1A1SMN1; SMN2MAPK1L3MBTL1
SCHEMBL13141810 0.76 MAPT (0.35) MAPTALDH1A1SMN1; SMN2NPSR1MAPK1
SCHEMBL13142215 0.75
SCHEMBL11660165 0.68 EPHX2 (0.40) MAPTALDH1A1SMN1; SMN2HSD11B1
SCHEMBL11658671 0.66 ERAP1 (0.46) MAPTALDH1A1TP53SMN1; SMN2MAPK1
SCHEMBL11807403 0.66 KDM4E (0.46) MAPTALDH1A1SMN1; SMN2NPSR1MAPK1
SCHEMBL3282366 0.65 LMNA (0.57) MAPTALDH1A1TP53SMN1; SMN2NPSR1
SCHEMBL3282369 0.65 LMNA (0.57) MAPTALDH1A1TP53SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940806-B2 Polymerizable compositions BASF SE (DE) 2015-01-27 US disclosed
US-20120041093-A1 POLYMERIZABLE COMPOSITIONS BASF SE (DE) 2012-02-16 US disclosed
WO-2010112410-A1 POLYMERIZABLE COMPOSITIONS BASF SE (DE) 2010-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041093-A1 POLYMERIZABLE COMPOSITIONS H1-10, CBR1, NR1H2 MAPT 3756/4885ALDH1A1 3185/4885TP53 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.