SCHEMBL10066451

SCHEMBL10066451

CCCc1cc(CC)ccn1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.55
NOS1 P29475 1/20 0.55
NOS2 P35228 1/20 0.55
KDM4E B2RXH2 3/20 0.55
LMNA P02545 3/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
SREBF2 Q12772 9/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 3/20 0.41
ATM Q13315 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 1/20 0.41
RECQL P46063 1/20 0.40
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487201 0.89 KDM4E (0.56) NOS3NOS1NOS2KDM4ELMNA
SCHEMBL2552826 0.88 NOS2 (0.52) NOS3NOS1NOS2KDM4ELMNA
SCHEMBL13337725 0.87 NOS3 (0.55) NOS3NOS1NOS2KDM4ELMNA
SCHEMBL31280277 0.86 NOS3 (0.50) NOS3NOS1NOS2KDM4ELMNA
SCHEMBL2550616 0.86 NOS3 (0.50) NOS3NOS1NOS2KDM4ELMNA
Hydrochloric Acid SCHEMBL11420925 0.85 NOS3 (0.53) NOS3NOS1NOS2KDM4ELMNA
SCHEMBL30019258 0.84 KCNH2 (0.48) NOS3NOS1NOS2KDM4ELMNA
SCHEMBL27630660 0.84 KCNH2 (0.48) NOS3NOS1NOS2KDM4ELMNA
SCHEMBL2555626 0.84 KCNH2 (0.48) NOS3NOS1NOS2KDM4ELMNA
Tetradecane SCHEMBL27660314 0.84 KCNH2 (0.48) NOS3NOS1NOS2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116263437-A Structure characterization method of aromatic nitrogen heterocyclic compound in petroleum fraction 中国石油天然气股份有限公司 2023-06-16 CN disclosed
WO-2022120355-A1 TEAD DEGRADERS AND USES THEREOF Ikena Oncology, Inc. (US) 2022-06-09 WO disclosed
EP-2900660-B1 HERBICIDAL AND FUNGICIDAL 3-HETEROARYLISOXAZOLIN-5-CARBOXAMIDES AND 3-HETEROARYLISOXAZOLIN-5-THIOAMIDES BAYER CROPSCIENCE AG (DE) 2018-01-17 EP disclosed
EP-2900644-B1 HERBICIDAL AND FUNGICIDAL 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-CARBOXAMIDES AND 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-THIOAMIDES BAYER CROPSCIENCE AG (DE) 2016-09-21 EP disclosed