Sugi Predict

Sugi Predict / Compounds / SCHEMBL487201

SCHEMBL487201

SCHEMBL487201

CCCc1ccnc(CCC)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.56
▸ LMNA P02545 3/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ TSHR P16473 1/20 0.56
▸ SREBF2 Q12772 10/20 0.44
▸ MAPT P10636 3/20 0.42
▸ ATM Q13315 3/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ NOS3 P29474 1/20 0.42
▸ NOS1 P29475 1/20 0.42
▸ NOS2 P35228 1/20 0.42
▸ CNR1 P21554 1/20 0.42
▸ CNR2 P34972 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ RECQL P46063 1/20 0.41
▸ CYP1A2 P05177 1/20 0.40
▸ POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2554060 0.90 KDM4E (0.47) KDM4ELMNACYP3A4TSHRSREBF2
SCHEMBL2619306 0.89 CYP1A2 (0.47) KDM4ELMNACYP3A4TSHRSREBF2
SCHEMBL10066451 0.89 NOS3 (0.55) KDM4ELMNACYP3A4TSHRSREBF2
SCHEMBL16544526 0.88 CYP3A4 (0.50) KDM4ELMNACYP3A4TSHRL3MBTL1
SCHEMBL2553622 0.88 CYP3A4 (0.46) KDM4ELMNACYP3A4TSHRL3MBTL1
SCHEMBL2555694 0.86 KCNH2 (0.48) KDM4ELMNACYP3A4TSHRL3MBTL1
SCHEMBL3638740 0.85 KDM4E (0.56) KDM4ELMNACYP3A4TSHRSREBF2
SCHEMBL5102581 0.85 KDM4E (0.47) KDM4ELMNACYP3A4TSHRSREBF2
SCHEMBL3640229 0.85 KDM4E (0.51) KDM4ELMNACYP3A4TSHRSREBF2
SCHEMBL27756399 0.85 KDM4E (0.51) KDM4ELMNACYP3A4TSHRSREBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328126-B2 Norbornenylhydrocarbylene dihydrocarbylboranes and methods of making the same PROMERUS, LLC (US) 2016-05-03 — — US claimed
US-20150353582-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME PROMERUS, LLC (US) 2015-12-10 — — US claimed
WO-2014121008-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME PROMERUS, LLC (US) 2014-08-07 — — WO claimed
US-8106200-B2 Pyridine borane complexes BASF SE (DE) 2012-01-31 — — US claimed
US-20110207934-A1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2011-08-25 — — US claimed
EP-2066631-B1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2011-04-06 — — EP claimed
CN-101516846-A Pyridine borane complexes BASF AG (DE) 2009-08-26 — — CN claimed
US-11707503-B2 Modulators of complement activity RA PHARMACEUTICALS, INC. (US) 2023-07-25 — — US disclosed
US-10189826-B2 Heterocyclic compounds and methods of use MEDIVATION TECHNOLOGIES LLC (US) 2019-01-29 — — US disclosed
US-10183015-B2 Heterocyclic compounds and methods of use MEDIVATION TECHNOLOGIES LLC (US) 2019-01-22 — — US disclosed
US-10066076-B1 Method for preparing conjugated diene polymer, composition comprising the same and tire comprising the composition LG CHEM, LTD. (KR) 2018-09-04 — — US disclosed
US-20180244892-A1 METHOD FOR PREPARING CONJUGATED DIENE POLYMER, COMPOSITION COMPRISING THE SAME AND TIRE COMPRISING THE COMPOSITION LG CHEM, LTD. (KR) 2018-08-30 — — US disclosed
US-20180193408-A1 MODULATORS OF COMPLEMENT ACTIVITY UCB HOLDINGS, INC. 2018-07-12 — — US disclosed
EP-2091956-A1 DIALKYLBORANE AMINE COMPLEXES BASF SE (DE) 2009-08-26 — — EP disclosed
EP-2066631-A1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2009-06-10 — — EP disclosed
WO-2008055859-A1 DIALKYLBORANE AMINE COMPLEXES BASF SE (DE) 2008-05-15 — — WO disclosed
WO-2008034886-A1 PYRIDINE BORANE COMPLEXES BASF SE (DE) 2008-03-27 — — WO disclosed
EP-0891970-B1 Process for producing alkenylsubstituted pyridine derivatives SUMITOMO CHEMICAL CO (JP) 2004-10-13 — — EP disclosed
US-6008364-A Process for producing alkenyl--substituted pyridine derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-28 — — US disclosed
EP-0891970-A1 Process for producing alkenylsubstituted pyridine derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-01-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707503-B2 Modulators of complement activity C3AR1, C1QBP, C5AR1 KDM4E 4540/4885LMNA 3987/4885CYP3A4 4400/4885
US-20150353582-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME CYP8B1, BDKRB1, CYP1B1 KDM4E 2351/4885LMNA 449/4885CYP3A4 446/4885
US-10189826-B2 Heterocyclic compounds and methods of use HRAS, VHL, ESRRB KDM4E 3356/4885LMNA 2671/4885CYP3A4 2057/4885
US-10183015-B2 Heterocyclic compounds and methods of use LIPC, CPT1A, FABP1 KDM4E 2233/4885LMNA 999/4885CYP3A4 484/4885
US-20180193408-A1 MODULATORS OF COMPLEMENT ACTIVITY C3AR1, C1QBP, C5AR1 KDM4E 4540/4885LMNA 3987/4885CYP3A4 4400/4885
US-20110207934-A1 PYRIDINE BORANE COMPLEXES NBAS, BRD8, PAXBP1 KDM4E 3906/4885LMNA 3308/4885CYP3A4 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.