Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.40 |
| ▸ | SCD | O00767 | 3/20 | 0.37 |
| ▸ | SCN1A | P35498 | 5/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239182 | 0.84 | ALDH1A1 (0.51) | GPR119SCDSCN1ASCN8ACSNK2A1 | |
| SCHEMBL1005456 | 0.83 | GPR119 (0.45) | GPR119SCN1ASCN8AKCNH2 | |
| SCHEMBL12239186 | 0.81 | SCD (0.42) | GPR119SCDSCN1ASCN8ACSNK2A1 | |
| SCHEMBL1006677 | 0.81 | GPR119 (0.44) | GPR119SCDSCN1ASCN8AKCNH2 | |
| SCHEMBL1007123 | 0.80 | GPR119 (0.42) | GPR119 | |
| SCHEMBL1005428 | 0.79 | SCD (0.47) | GPR119SCDCSNK2A1KCNH2 | |
| SCHEMBL12239188 | 0.79 | GPR119 (0.42) | GPR119SCDSCN1ASCN8ACSNK2A1 | |
| SCHEMBL12239172 | 0.79 | SMN1; SMN2 (0.43) | GPR119SCDSCN1ASCN8ACSNK2A1 | |
| SCHEMBL1003971 | 0.78 | SCD (0.46) | GPR119SCDCSNK2A1KCNH2 | |
| SCHEMBL12262498 | 0.77 | SCN8A (0.42) | GPR119SCDSCN1ASCN8ACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271619-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009126535-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |