Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239172 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2CSNK2A1GPR119SCDHRH3 | |
| SCHEMBL1005456 | 0.84 | GPR119 (0.45) | KDM4EGPR119SCN1ASCN8A | |
| SCHEMBL1006689 | 0.84 | GPR119 (0.40) | ALDH1A1CSNK2A1GPR119SCDSCN1A | |
| SCHEMBL12239186 | 0.84 | SCD (0.42) | SMN1; SMN2CSNK2A1GPR119SCDSCN1A | |
| SCHEMBL1005428 | 0.83 | SCD (0.47) | CSNK2A1GPR119SCD | |
| SCHEMBL12239176 | 0.83 | CSNK2A1 (0.45) | CSNK2A1GPR119SCDSCN1ASCN8A | |
| SCHEMBL12239179 | 0.83 | GPR119 (0.44) | CSNK2A1GPR119SCD | |
| SCHEMBL1003971 | 0.82 | SCD (0.46) | CSNK2A1GPR119SCD | |
| SCHEMBL12262498 | 0.81 | SCN8A (0.42) | SMN1; SMN2CSNK2A1GPR119SCDSCN1A | |
| SCHEMBL12239188 | 0.81 | GPR119 (0.42) | SMN1; SMN2CSNK2A1GPR119SCDSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | ALDH1A1 2341/4885MAPT 4750/4885CRHBP 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.