Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066176 | 0.89 | MAPT (0.46) | ROCK2ENPP2F10KLKB1KLK1 | |
| SCHEMBL10066415 | 0.78 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL31022773 | 0.71 | MKNK1 (0.46) | MKNK1MKNK2 | |
| SCHEMBL12316835 | 0.71 | MKNK1 (0.46) | MKNK1MKNK2 | |
| SCHEMBL3647370 | 0.68 | ALDH1A1 (0.64) | NPC1RECQL | |
| SCHEMBL27823198 | 0.68 | RECQL (0.70) | NPC1RECQLKLKB1KLK1MKNK1 | |
| SCHEMBL608617 | 0.67 | KMO (0.73) | MKNK1MKNK2ATR | |
| SCHEMBL7445061 | 0.66 | F7 (0.59) | RECQLMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL30037096 | 0.66 | KMO (0.71) | MKNK1MKNK2ATR | |
| SCHEMBL30005873 | 0.66 | F10 (0.59) | ROCK2ENPP2RECQLF10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006203-A1 | N-CYCLYL-3 - (CYCLYLCARBONYLAMINOMETHYL) BENZAMIDE DERIVATIVES AS RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-12 | — | — | WO | disclosed |