Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879553 | 0.85 | MAPT (0.47) | NPSR1PTGESMEN1KMT2APDE2A | |
| SCHEMBL10067206 | 0.81 | TAS2R14 (0.39) | MEN1KMT2ATAS2R14CYP1A2CYP2C19 | |
| SCHEMBL10067207 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2ATAS2R14CYP1A2CYP2C19 | |
| SCHEMBL14963063 | 0.74 | LMNA (0.41) | PTGESMEN1KMT2ATP53KDM4E | |
| SCHEMBL12885976 | 0.71 | MEN1 (0.53) | NPSR1MEN1PKMKMT2ATAS2R14 | |
| SCHEMBL14014922 | 0.70 | MEN1 (0.50) | NPSR1MEN1PKMKMT2AKDM4E | |
| SCHEMBL13696457 | 0.68 | KDM1A (0.40) | TAS2R14PDE2AKCNJ6KCNJ3 | |
| SCHEMBL14393648 | 0.67 | NOTUM (0.38) | MEN1KMT2ATAS2R14PDE2AKDM4E | |
| SCHEMBL13543373 | 0.67 | ACACB (0.36) | PTGESMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13753374 | 0.67 | JAK2 (0.57) | NPSR1MEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059587-B1 | LACCASES FOR PULP BIO-BLEACHING | VERENIUM CORP (US) | 2012-01-04 | — | — | EP | disclosed |
| WO-2008027501-A2 | LACCASES FOR PULP BIO-BLEACHING | VERENIUM CORPORATION (US) | 2008-03-06 | — | — | WO | disclosed |