SCHEMBL13543373

SCHEMBL13543373

Cc1ccc(Cl)c(N(O)C(=O)NC(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACACB O00763 1/20 0.36
▸ PTGES O14684 1/20 0.36
▸ MAPK1 P28482 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ TAS1R3 Q7RTX0 2/20 0.35
▸ TAS1R1 Q7RTX1 2/20 0.35
▸ TAS1R2 Q8TE23 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HPGD P15428 2/20 0.34
▸ MAPT P10636 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ PDK1 Q15118 1/20 0.34
▸ PDK2 Q15119 1/20 0.34
▸ PDK3 Q15120 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL879553 0.80 MAPT (0.47) ACACBPTGESMEN1KMT2ALMNA
SCHEMBL13543374 0.79 RAB9A (0.42) MEN1HSP90AA1KMT2ATAS1R3TAS1R1
SCHEMBL19483171 0.77 FSCN1 (0.40) MEN1HSP90AA1KMT2ATAS1R3TAS1R1
SCHEMBL13543371 0.77 RAB9A (0.47) MEN1KMT2AHPGDNPC1RAB9A
SCHEMBL13886794 0.74 ITGB1 (0.47) MEN1KMT2ALMNAHPGDMAPT
SCHEMBL14963063 0.71 LMNA (0.41) PTGESMEN1KMT2ALMNAHPGD
SCHEMBL11444990 0.69 ALDH1A1 (0.54) PTGESHPGDMAPTNPC1RAB9A
SCHEMBL28900775 0.69 LMNA (0.42) PTGESMAPK1MEN1KMT2ATAS1R3
SCHEMBL11811760 0.68 ALDH1A1 (0.42) MEN1KMT2AHPGDSMN1; SMN2ALDH1A1
SCHEMBL11513064 0.68 LMNA (0.41) PTGESMAPK1MEN1KMT2ATAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9677053-B2 Laccases for bio-bleaching BASF ENZYMES LLC (US) 2017-06-13 — — US disclosed
US-20160237411-A1 LACCASES FOR BIO-BLEACHING VERENIUM CORPORATION 2016-08-18 — — US disclosed
US-9353477-B2 Laccases for bio-bleaching BASF ENZYMES LLC (US) 2016-05-31 — — US disclosed
US-20150125936-A1 LACCASES FOR BIO-BLEACHING BASF SE (DE) 2015-05-07 — — US disclosed
US-8951766-B2 Laccases for bio-bleaching BASF ENZYMES LLC (US) 2015-02-10 — — US disclosed
US-20130126110-A1 LACCASES FOR BIO-BLEACHING BASF SE (DE) 2013-05-23 — — US disclosed
US-8377670-B2 Laccases for bio-bleaching VERENIUM CORPORATION (US) 2013-02-19 — — US disclosed
US-20100018658-A1 Laccases for Bio-Bleaching VERENIUM CORPORATION (US) 2010-01-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100018658-A1 Laccases for Bio-Bleaching AOX1, GUSB, LPO ACACB 665/4885PTGES 2288/4885MAPK1 3054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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