SCHEMBL1006743

SCHEMBL1006743

CC(C)c1cccc(C(C)C)c1N1CCSC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 6/20 0.39
ANPEP P15144 5/20 0.39
GABRA1 P14867 3/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRB2 P47870 2/20 0.36
FAAH O00519 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
GABRB1 P18505 1/20 0.36
PTGS1 P23219 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL456981 0.75 GABRA1 (0.43) DPP4ANPEPGABRA1GABRG2GABRB3
SCHEMBL8990154 0.75 GABRA1 (0.43) DPP4ANPEPGABRA1GABRG2GABRB3
Hydrochloric Acid SCHEMBL739371 0.73 GABRA1 (0.41) DPP4ANPEPGABRA1GABRG2GABRB3
Hydrochloric Acid SCHEMBL1727636 0.72 DPP4 (0.40) DPP4ANPEPGABRA1GABRG2GABRB3
SCHEMBL30645698 0.71 FAAH (0.40) FAAH
SCHEMBL17435861 0.70 ADRB1 (0.44) CYP1A2CYP3A4TSHRHTR2CHTR2B
SCHEMBL19440976 0.70 ADRB1 (0.35) DPP4LMNAHPGDTSHRMEN1
SCHEMBL14221891 0.70 GABRA1 (0.46) DPP4ANPEPGABRA1GABRG2GABRB3
SCHEMBL28325603 0.69 DPP4 (0.40) DPP4ANPEPGABRA1GABRG2GABRB3
SCHEMBL29523444 0.69 DPP4 (0.41) DPP4ANPEPGABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127520-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2018-05-10 US disclosed
US-9850325-B2 Method for producing ring-opening metathesis polymer hydride, and resin composition ZEON CORPORATION (JP) 2017-12-26 US disclosed
EP-2270063-B1 PROCESS FOR PRODUCING HYDROGENATED PRODUCT OF CYCLIC OLEFIN POLYMER PREPARED THROUGH RING-OPENING POLYMERIZATION ZEON CORP (JP) 2016-03-23 EP disclosed
US-20150051353-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2015-02-19 US disclosed
EP-2826802-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION Zeon Corporation (JP) 2015-01-21 EP disclosed
EP-1197509-B1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN ZEON CORP (JP) 2011-07-06 EP disclosed
EP-2270063-A2 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization NIPPON ZEON CO., LTD. (JP) 2011-01-05 EP disclosed
EP-1275675-B1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE ZEON CORP (JP) 2005-12-07 EP disclosed
US-6908970-B2 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION (JP) 2005-06-21 US disclosed
US-6815516-B2 HEAT RESISTANCE, SOLVENT SOLUBILITY ZEON CORPORATION (JP) 2004-11-09 US disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed