Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL739371 | 0.98 | GABRA1 (0.41) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| Hydrochloric Acid SCHEMBL1727636 | 0.96 | DPP4 (0.40) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL20408268 | 0.91 | HTR7 (0.43) | FAAHDPP4NR1H2NR1H3ALDH1A1 | |
| SCHEMBL17505334 | 0.89 | GABRA1 (0.39) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL29523444 | 0.88 | DPP4 (0.41) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL1047507 | 0.86 | ALDH1A1 (0.39) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL16385896 | 0.86 | HTR1A (0.39) | GABRA1GABRG2GABRB3LMNAHTR2C | |
| Hydrochloric Acid SCHEMBL29070208 | 0.85 | DPP4 (0.36) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| Hydrochloric Acid SCHEMBL820072 | 0.85 | ALDH1A1 (0.38) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| Hydrochloric Acid SCHEMBL1609149 | 0.85 | ADRB1 (0.44) | TSHRLMNAHPGDALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 669 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024256574-A1 | PROCESS FOR PREPARING MACROCYCLIC BTK INHIBITORS | CROSSFIRE ONCOLOGY HOLDING B.V. (NL) | 2024-12-19 | — | — | WO | claimed |
| CN-118562303-A | Composition of high-pressure-resistant VW-1 flame-retardant silicone rubber | 力元材料科技(广东)有限公司 | 2024-08-30 | — | — | CN | claimed |
| EP-3016991-B1 | LIQUID MOLDING COMPOSITIONS | MATERIA INC (US) | 2024-06-12 | — | — | EP | claimed |
| US-20240116039-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2024-04-11 | — | — | US | claimed |
| CN-117843428-A | endo/exo 3, 4-disubstituted tricyclo [4.2.1.0 2,5 ]Process for preparing non-3, 7-diene compound | 湖南师范大学 | 2024-04-09 | — | — | CN | claimed |
| EP-3256505-B1 | CYCLIC OLEFIN RESIN COMPOSITIONS COMPRISING FUNCTIONAL ELASTOMERS | MATERIA INC (US) | 2023-11-29 | — | — | EP | claimed |
| CN-116802187-A | Organometallic compounds | 优米科尔股份公司及两合公司 | 2023-09-22 | — | — | CN | claimed |
| US-20230149911-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | UMICORE AG & CO. KG (DE) | 2023-05-18 | — | — | US | claimed |
| US-11577232-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | UMICORE AG & CO. KG (DE) | 2023-02-14 | — | — | US | claimed |
| CN-114502558-A | Method for preparing activin receptor-like kinase inhibitors | 缆图药品公司 | 2022-05-13 | — | — | CN | claimed |
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2009-03-12 | — | — | US | claimed |
| US-20090062475-A1 | Production of elastomeric functionalized olefin polymers | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2009-03-05 | — | — | US | claimed |
| US-20080312393-A1 | Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof | BAUGH LISA S | 2008-12-18 | — | — | US | claimed |
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | claimed |
| EP-1885669-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | Promerus LLC (US) | 2008-02-13 | — | — | EP | claimed |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2006-12-21 | — | — | US | claimed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | claimed |
| EP-1704172-A1 | LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF | ExxonMobil Research and Engineering Company (US) | 2006-09-27 | — | — | EP | claimed |
| WO-2005063834-A1 | LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-07-14 | — | — | WO | claimed |
| US-20050137369-A1 | Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2005-06-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149911-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRB2 1560/4885GABRG2 3496/4885 |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | NDC1, DDC, PDCD1LG2 | GABRA1 3435/4885GABRB2 2368/4885GABRG2 3152/4885 |
| US-11577232-B2 | Ruthenium-based metathesis catalysts, precursors for their preparation and their use | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRB2 1560/4885GABRG2 3496/4885 |
| US-20240116039-A1 | RUTHENIUM-BASED METATHESIS CATALYSTS, PRECURSORS FOR THEIR PREPARATION AND THEIR USE | HMBS, RRP12, RNF168 | GABRA1 3066/4885GABRB2 1560/4885GABRG2 3496/4885 |
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | PF4, AFF4, FLI1 | GABRA1 74/4885GABRB2 86/4885GABRG2 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.