Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | RORA | P35398 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | RORB | Q92753 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067482 | 0.93 | TDP1 (0.41) | MAPTKDM4EGAAHSD17B10POLB | |
| SCHEMBL19075299 | 0.89 | KDM4E (0.46) | MAPTKDM4EHSD17B10POLBPGR | |
| SCHEMBL14176722 | 0.89 | TDP1 (0.39) | MAPTKDM4EGAAPOLBPGR | |
| SCHEMBL18830662 | 0.88 | KDM4E (0.40) | MAPTKDM4EHSD17B10POLBPGR | |
| SCHEMBL19075295 | 0.88 | DNM1 (0.44) | MAPTKDM4EGAAHSD17B10POLB | |
| SCHEMBL18830613 | 0.88 | ALDH1A1 (0.41) | MAPTKDM4EGAAHSD17B10POLB | |
| SCHEMBL30434963 | 0.88 | PGR (0.42) | MAPTKDM4EGAAHSD17B10POLB | |
| SCHEMBL29009241 | 0.88 | PGR (0.42) | MAPTKDM4EGAAHSD17B10POLB | |
| SCHEMBL10101135 | 0.87 | TDP1 (0.38) | MAPTKDM4EGAAPOLBPGR | |
| SCHEMBL9913062 | 0.86 | POLB (0.46) | MAPTKDM4EGAAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802594-B1 | METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |
| US-8535863-B2 | Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same | RICOH COMPANY, LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| US-8535863-B2 | Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same | RICOH COMPANY, LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| US-20120052424-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME | RICOH COMPANY, LTD. (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120052424-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME | RICOH COMPANY, LTD. (JP) | 2012-03-01 | — | — | US | disclosed |