SCHEMBL10067482

SCHEMBL10067482

CCc1ccc(-n2c3ccc(C)cc3c3cc(C)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
APOBEC3G Q9HC16 1/20 0.41
KDM4E B2RXH2 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MGLL Q99685 1/20 0.38
USP14 P54578 1/20 0.37
PGR P06401 1/20 0.37
RORA P35398 1/20 0.37
RORC P51449 1/20 0.37
RORB Q92753 1/20 0.37
POLB P06746 1/20 0.37
TP53 P04637 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HCAR1 Q9BXC0 1/20 0.36
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14176722 0.95 TDP1 (0.39) TDP1APOBEC3GKDM4EGAAMAPT
SCHEMBL10101135 0.94 TDP1 (0.38) TDP1APOBEC3GKDM4EGAAMAPT
SCHEMBL10067484 0.93 MAPT (0.40) TDP1APOBEC3GKDM4EGAAMAPT
SCHEMBL4570430 0.87 POLB (0.38) KDM4EGAAMAPTMGLLUSP14
SCHEMBL10013270 0.87 ALDH1A1 (0.40) TDP1KDM4EGAAMAPTPGR
SCHEMBL30434963 0.87 PGR (0.42) TDP1APOBEC3GKDM4EGAAMAPT
SCHEMBL29009241 0.87 PGR (0.42) TDP1APOBEC3GKDM4EGAAMAPT
SCHEMBL15025823 0.87 POLB (0.44) TDP1KDM4EGAAMAPTUSP14
SCHEMBL9913062 0.85 POLB (0.46) TDP1KDM4EGAAMAPTUSP14
SCHEMBL14948445 0.84 USP14 (0.36) KDM4EGAAMAPTUSP14PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-8471143-B2 Photoelectric conversion element and solar cell KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-06-25 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed
US-20100282322-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-11-11 US disclosed
US-20080054794-A1 Organic Electroluminescence Device, Image Display Apparatus and Lighting Apparatus Including the Same, Charge Transport Material and Charge Transport Layer Forming Ink Including the Same Fujiki, Michiya (JP) 2008-03-06 US disclosed