SCHEMBL1006775

SCHEMBL1006775

CCN(CC)C(Br)C(=O)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.66
ADRA2A P08913 1/20 0.66
ADRA2B P18089 1/20 0.66
HTR2A P28223 1/20 0.66
HRH1 P35367 1/20 0.66
KCNH2 Q12809 1/20 0.66
MAPT P10636 2/20 0.45
NPC1 O15118 1/20 0.45
MAPK1 P28482 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
MDM2 Q00987 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
CES2 O00748 3/20 0.41
CES1 P23141 3/20 0.41
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11109809 0.83 PGR (0.68) PGRADRA2AADRA2BHTR2AHRH1
Diethylpropion SCHEMBL27330 0.79 PGR (1.00) PGRADRA2AADRA2BHTR2AHRH1
Diethylpropion SCHEMBL15484 0.79 PGR (1.00) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL29273682 0.79 RAB9A (0.49) PGRADRA2AADRA2BHTR2AHRH1
Diethylpropion SCHEMBL506145 0.78 PGR (0.96) PGRADRA2AADRA2BHTR2AHRH1
Diethylpropion SCHEMBL22614735 0.78 PGR (0.96) PGRADRA2AADRA2BHTR2AHRH1
SCHEMBL11104030 0.78 PGR (0.66) PGRADRA2AADRA2BHTR2AHRH1
Diethylpropion SCHEMBL15483 0.78 PGR (0.96) PGRADRA2AADRA2BHTR2AHRH1
Diethylpropion SCHEMBL7715371 0.78 PGR (0.96) PGRADRA2AADRA2BHTR2AHRH1
Diethylpropion SCHEMBL5546846 0.76 PGR (0.93) PGRADRA2AADRA2BHTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011003193-A1 COMPOUNDS AND METHODS FOR DETECTION AND QUANTIFICATION OF CARBOXYLIC ACIDS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2011-01-13 WO disclosed