Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068163 | 0.87 | MAPK13 (0.57) | MAPK13MAPK12MAPK11MAPK14KDM4E | |
| SCHEMBL10079027 | 0.81 | NPC1 (0.58) | SMN1; SMN2RAB9ANPC1MEN1HPGD | |
| SCHEMBL10068142 | 0.81 | EPHX1 (0.49) | GSK3BSMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL10082146 | 0.80 | MAP3K5 (0.53) | MAP3K5KDM4EGSK3BSMN1; SMN2RAB9A | |
| SCHEMBL22822777 | 0.78 | RAB9A (0.50) | KDM4EGSK3BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29177265 | 0.78 | RAB9A (0.49) | KDM4ESMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL10068151 | 0.77 | HTT (0.54) | SMN1; SMN2RAB9ANPC1HTTALDH1A1 | |
| SCHEMBL10068162 | 0.77 | PIK3CG (0.45) | KDM4ESMN1; SMN2RAB9AMEN1HPGD | |
| SCHEMBL10068161 | 0.77 | RAB9A (0.49) | KDM4EGSK3BSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10068156 | 0.76 | ALDH1A1 (0.60) | SMN1; SMN2RAB9ANPC1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | MAPK13 3318/4885MAPK12 3715/4885MAPK11 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.