Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068437 | 1.00 | KDM4E (0.38) | KDM4ECA3CA5ACA5BCA12 | |
| SCHEMBL10068433 | 0.80 | CASP2 (0.41) | KDM4EMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18270932 | 0.80 | ALDH1A1 (0.46) | ALDH1A1PAOXHDAC1HDAC2ZDHHC20 | |
| SCHEMBL16748699 | 0.79 | CASP2 (0.46) | ALDH1A1HDAC1HDAC2ZDHHC20ZDHHC2 | |
| SCHEMBL10068435 | 0.76 | TSHR (0.43) | KDM4ECA3CA5ACA5BCA12 | |
| SCHEMBL10068431 | 0.76 | TSHR (0.43) | KDM4ECA3CA5ACA5BCA12 | |
| SCHEMBL10063646 | 0.73 | MAPT (0.43) | KDM4ECA3CA5ACA5BCA12 | |
| SCHEMBL9363613 | 0.73 | CA12 (0.50) | CA3CA5ACA5BCA12CA2 | |
| Hydrochloric Acid SCHEMBL9507179 | 0.72 | LMNA (0.52) | CA3CA5ACA5BCA12CA2 | |
| SCHEMBL9363619 | 0.71 | CA12 (0.54) | CA3CA5ACA5BCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778858-B2 | Amine derivatives as friction modifiers in lubricants | THE LUBRIZOL CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-20120015855-A1 | Amine Derivatives as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION | 2012-01-19 | — | — | US | disclosed |