Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068431 | 1.00 | TSHR (0.43) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL10068430 | 0.87 | TSHR (0.50) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL12791500 | 0.84 | TSHR (0.59) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL29915714 | 0.80 | TSHR (0.59) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL23085540 | 0.78 | TSHR (0.64) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL24263795 | 0.78 | MAOA (0.55) | TSHRKDM4ECA12CA14ALDH1A1 | |
| SCHEMBL72889 | 0.78 | TSHR (0.67) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL10038845 | 0.77 | TSHR (0.50) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL10038847 | 0.77 | TSHR (0.50) | TSHRKDM4ECA12CA14EPHX2 | |
| SCHEMBL10068434 | 0.76 | KDM4E (0.38) | KDM4ECA12CA14ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778858-B2 | Amine derivatives as friction modifiers in lubricants | THE LUBRIZOL CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-20120015855-A1 | Amine Derivatives as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION | 2012-01-19 | — | — | US | disclosed |
| WO-2010096325-A1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |