SCHEMBL23085540

SCHEMBL23085540

COC(=O)CCCNCCC(=O)OC

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.64
CA12 O43570 4/20 0.50
CA14 Q9ULX7 4/20 0.50
ALDH1A1 P00352 2/20 0.45
LMNA P02545 2/20 0.45
EPHX2 P34913 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA2 P00918 1/20 0.43
LTA4H P09960 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14430277 0.95 TSHR (0.70) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL12791500 0.93 TSHR (0.59) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL29915714 0.93 TSHR (0.59) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL72889 0.90 TSHR (0.67) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL10042464 0.87 TSHR (0.63) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL12847508 0.87 TSHR (0.63) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL23792741 0.86 TSHR (0.52) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL5001750 0.86 CA12 (0.61) TSHRCA12CA14ALDH1A1EPHX2
SCHEMBL24263734 0.86 TSHR (0.58) TSHRCA12CA14ALDH1A1LMNA
SCHEMBL2586098 0.86 TSHR (0.64) TSHRCA12CA14ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719602-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-04-08 EP disclosed
US-20250051375-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. 2025-02-13 US disclosed
WO-2024249517-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. (US) 2024-12-05 WO disclosed
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-20210228727-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2021-07-29 US disclosed
US-20210220478-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2021-07-22 US disclosed
WO-2021046549-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2021-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A TSHR 2184/4885CA12 399/4885CA14 220/4885
US-20210228727-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A TSHR 2184/4885CA12 399/4885CA14 220/4885
US-20250051375-A1 ANTI-HIV COMPOUNDS CCR5, CD4, NFATC1 TSHR 4882/4885CA12 4488/4885CA14 4190/4885
US-11833213-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A TSHR 2184/4885CA12 399/4885CA14 220/4885
US-20210220478-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A TSHR 2184/4885CA12 399/4885CA14 220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.