Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 10/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67738 | 0.84 | ADK (0.55) | ADKPRMT5WDR77DOT1LNPC1 | |
| SCHEMBL90991 | 0.84 | ADK (0.55) | ADKPRMT5WDR77DOT1LNPC1 | |
| SCHEMBL91053 | 0.80 | ADK (0.59) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL90994 | 0.77 | HINT1 (0.41) | ADKPRMT5WDR77DOT1LPRMT3 | |
| SCHEMBL24191528 | 0.76 | ADK (0.51) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL10067432 | 0.75 | ADK (0.48) | ADKPRMT5DOT1LDNMT1METTL3 | |
| SCHEMBL31617792 | 0.70 | DOT1L (0.69) | PRMT5WDR77DOT1LAHCY | |
| SCHEMBL25047821 | 0.70 | DOT1L (0.69) | PRMT5WDR77DOT1LAHCY | |
| SCHEMBL6685798 | 0.69 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL25027456 | 0.68 | ADK (0.69) | ADKDOT1LNPC1GALR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756313-B1 | SEQUENCE-SPECIFIC DETECTION OF METHYLATION IN BIOMOLECULES | MAX PLANCK GESELLSCHAFT (DE) | 2012-06-06 | — | — | EP | disclosed |