Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 18/20 | 0.59 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67738 | 0.90 | ADK (0.55) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL90991 | 0.90 | ADK (0.55) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL25027456 | 0.87 | ADK (0.69) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL12522464 | 0.81 | ADK (0.60) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL10069367 | 0.80 | ADK (0.49) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL6685798 | 0.79 | ADK (0.71) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL59610 | 0.78 | DPP4 (0.74) | DOT1L | |
| SCHEMBL173151 | 0.78 | DPP4 (0.74) | DOT1L | |
| SCHEMBL13986299 | 0.78 | DPP4 (0.74) | DOT1L | |
| SCHEMBL8333514 | 0.74 | ADK (1.00) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129106-B2 | Sequence-specific detection of methylation in biomolecules | Max-Planck-Geselischaft zur Forderung der Wissenschaften E.V. (DE) | 2012-03-06 | — | — | US | disclosed |